I’ll kick things off with my own experience.
I’ve used both Tirzepatide and Retatrutide.
For me, Tirzepatide has noticeably stronger appetite suppression. Even after increasing my Retatrutide dose, I still found myself thinking about food more than I did on Tirzepatide.
On the other hand, I feel like I have more energy on Retatrutide, which has made sticking to my workouts and staying active easier.
One interesting side effect I had with Retatrutide was skin sensitivity when I reached around 5 mg/week. It wasn’t painful, but my skin felt unusually sensitive to touch. Fortunately, it gradually disappeared after a few weeks.
Because appetite control wasn’t quite as strong for me, I’ve been stacking a low dose of Cagrilintide with Retatrutide, and that combination has worked very well.
Everyone seems to respond a little differently, so I’m interested to hear what others have experienced. If you’ve tried both, which one would you choose, and why?