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  • I’ll kick things off with my own experience.

    I’ve used both Tirzepatide and Retatrutide.

    For me, Tirzepatide has noticeably stronger appetite suppression. Even after increasing my Retatrutide dose, I still found myself thinking about food more than I did on Tirzepatide.

    On the other hand, I feel like I have more energy on Retatrutide, which has made sticking to my workouts and staying active easier.

    One interesting side effect I had with Retatrutide was skin sensitivity when I reached around 5 mg/week. It wasn’t painful, but my skin felt unusually sensitive to touch. Fortunately, it gradually disappeared after a few weeks.

    Because appetite control wasn’t quite as strong for me, I’ve been stacking a low dose of Cagrilintide with Retatrutide, and that combination has worked very well.

    Everyone seems to respond a little differently, so I’m interested to hear what others have experienced. If you’ve tried both, which one would you choose, and why?